Articles

TIME OF EXCHANGE OF 131 I-LABELED ALBUMIN BETWEEN PLASMA AND PERIPHERAL LYMPH IN MAN

Authors
  • A Engeset
  • M Aas
  • W Olszewski
  • J Sokolowski

Abstract

The passage from blood to peripheral lymph of 131 I-labeled human serum albumin has been studied in 6 male patients (30 - 70 years) with malignancies without metastases. On the first day the concentration of radio-labeled albumin in the blood was kept almost constant by repeated i.v. injections. Lymph was collected continuously from a cannulated subcutaneous lymph vessel on the leg.

Two hours after the first i.v. injection of radio-labeled albumin the lymph contained significant amounts of radioactivity in all patients. Equilibrium between radioactivity in blood and lymph was reached after 26 hrs. This indicates a long "wash out time" of unlabeled protein in the interstitial tissue from where lymph has been sampled.

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How to Cite:

Engeset, A. & Aas, M. & Olszewski, W. & Sokolowski, J., (1979) “TIME OF EXCHANGE OF 131 I-LABELED ALBUMIN BETWEEN PLASMA AND PERIPHERAL LYMPH IN MAN”, Lymphology 12(2), p.77-80.

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Published on
25 Sep 1979
Peer Reviewed