TIME OF EXCHANGE OF 131 I-LABELED ALBUMIN BETWEEN PLASMA AND PERIPHERAL  LYMPH IN  MAN

A Engeset; M Aas; W Olszewski; J Sokolowski

Articles

TIME OF EXCHANGE OF 131 I-LABELED ALBUMIN BETWEEN PLASMA AND PERIPHERAL LYMPH IN MAN

Authors: A Engeset ( ) , M Aas ( ) , W Olszewski ( ) , J Sokolowski ( )

Abstract

The passage from blood to peripheral lymph of 131 I-labeled human serum albumin has been studied in 6 male patients (30 - 70 years) with malignancies without metastases. On the first day the concentration of radio-labeled albumin in the blood was kept almost constant by repeated i.v. injections. Lymph was collected continuously from a cannulated subcutaneous lymph vessel on the leg.

Two hours after the first i.v. injection of radio-labeled albumin the lymph contained significant amounts of radioactivity in all patients. Equilibrium between radioactivity in blood and lymph was reached after 26 hrs. This indicates a long "wash out time" of unlabeled protein in the interstitial tissue from where lymph has been sampled.

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How to Cite: Engeset, A. , Aas, M. , Olszewski, W. & Sokolowski, J. (1979) “TIME OF EXCHANGE OF 131 I-LABELED ALBUMIN BETWEEN PLASMA AND PERIPHERAL LYMPH IN MAN”, Lymphology. 12(2).