Articles

Radiographic Features of Hodgkin's Disease

Authors
  • J.W Davidson
  • E.A Clarke

Abstract

1. Radiographic morphology and morphometry of retroperitoneal lymph nodes has been described in patients with each of the common presenting histological subtypes of Hodgkin's Disease.

2. In addition to well known lymphographic features of Hodgkin's Disease many less florid changes have been described in the radio-opaque images of pelvic and retroperitoneal lymph glands. Such non-specific findings have been seen in the absence of histological evidence of Hodgkin's Disease in the same nodes, and may be related to abnormal lymphoreticular function preceding or concurrent with early neoplastic changes (19). Their significance with respect to immune mechanisms is not yet known.

3. Because of current ignorance of the basic pathogenesis of Hodgkin's Disease, in vivo lymphographic study of contrast containing intranodal sinusoids of many glands, and in vitro histological study of individual lymph node samples obtained at biopsy or laparotomy evaluate different parameters of abnormality, and are at present complementary.

4. In this series lymph node architecture and the topography of adenopathy suggest two distinct patterns of involvement in Hodgkin's Disease.

5. A practical method of dividing the majority of new patients with Hodgkin's Disease into two groups for further study is described.

How to Cite:

Davidson, J. & Clarke, E., (1972) “Radiographic Features of Hodgkin's Disease”, Lymphology 5(3), 95-106.

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Published on
29 Sep 1972
Peer Reviewed