Articles

Topical treatment of acute hindlimb lymphedema of the rat using a troxerutin-phosphatidylcholine complex in liposomal-like microdispersion

Authors
  • JR Casley-Smith
  • J.R Casley-Smith
  • S Curri
  • M Foldi

Abstract

A new reversible complex between troxerutin and phosphatidylcholine (85-90mg/kg per day), in the form of a liposome-like water microdispersion, was topically applied to the rat thigh in an experimental counterpart of acute lymphedema. After four days there was 75% less hindlimb edema (mean decrease 40% of normal compared to control 10% of normal) in the treated compared with the untreated rats. These findings suggest that this drug preparation may be useful to minimize acute peripheral lymphedema in patients.

How to Cite:

Casley-Smith, J. & Casley-Smith, J. & Curri, S. & Foldi, M., (1993) “Topical treatment of acute hindlimb lymphedema of the rat using a troxerutin-phosphatidylcholine complex in liposomal-like microdispersion”, Lymphology 26(1), 25-27.

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Published on
07 Sep 1993
Peer Reviewed