Articles

LYMPHATIC AND VENOUS TRANSPORT OF COLLOIDS FROM THE TISSUES

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Abstract

Colloid molecules injected into the tissues are absorbed both by lymphatic and blood capillaries. In dogs with cannulated thoracic duct, 94% of I¹³¹-albumin injected into the renal cortex was recovered within 1 min in renal venous blood, after 5 min, 90% of Cr⁵¹ labelled blood corpuscles was found in circulating blood. In 6 hours, 5.4 ± 1. 7% of albumin and 11.1 ± 1.5 of Au¹⁹⁸ -colloid, (diam. 300-700 Å) injected into the myocardium is transported by the lymphatics, 35% of the albumin was found in circulating plasma and 8.6 ± 1.2 of the gold colloid was recovered in plasma and liver. From the pancreas, 7.2 ± 2.0% of the albumin and 7.0 ± 0.5% pf the gold colloid was transported by the lymphatics, and 12.3% (albumin} and 1.2 ± 0.4% (Au ^198-coIL) by blood capillaries. Lymphatic transport of the gold colloid from the intestinal wall was 15.9 ± 1.9% recovery in liver and plasma 1.4 ± 0.8%. From contracting skeletal muscle, lymphatic transport of albumin was 40.1 ± 3.5% and of gold colloid 4.6 ± 0.72%. Recovery of albumin in circulating plasma was 3.7% of gold colloid in plasma and liver 0.5 ± 0.1%. From the subcutis, 21.6 ± 6.2% of albumin is transported by lymphatics, 11% by blood capillaries. Tissue pressure increased during injection but preinjection values were reestablished within 2 to 5 minutes. Accordingly, tissue pressure changes do not play a dominant role in colloid absorption.

How to Cite:

Szabo, G., Magyar, Z. & Molnar, G., (1973) “LYMPHATIC AND VENOUS TRANSPORT OF COLLOIDS FROM THE TISSUES”, Lymphology 6(2), 69-79.