ENHANCED PROSTAGLANDIN I2-FORMATION OF HUMAN LYMPHATICS DURING PULSATILE PERFUSION
- H Sinzinger
- J Kaliman
- E Mannheimer
Abstract
Previous studies demonstrate that prostacyclin (prostaglandin I2, PGI2) is the main arachidonic acid product in human lymph vessels. Pulsatile perfusion increases and prolongs PGirfarmation as do leukotrienes (LT) such as LTC4. Thus, physical activity besides local mechanical and biochemical influences on lymph pressure and flow also stimulates local lymphatic PGI2 synthesis, a prime counterbalancing factor in lymphatic constriction induced by other eicosanoids.
How to Cite:
Sinzinger, H., Kaliman, J. & Mannheimer, E., (1986) “ENHANCED PROSTAGLANDIN I2-FORMATION OF HUMAN LYMPHATICS DURING PULSATILE PERFUSION”, Lymphology 19(4), 153-156.
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