CONTRIBUTION OF PLASMA PROTEIN AND LIPOPROTEINS TO INTESTINAL LYMPH: COMPARISON OF LONG-CHAIN WITH MEDIUM-CHAIN TRIGLYCERIDE DUODENAL INFUSION
- AM Sipahi
- HCF Oliveira
- KS Vasconcelos
- LN Castilho
- A Bettarello
- ECR Quintao
Abstract
In rats with intestinal lymph-fistula and electrolyte and protein losses continuously replaced by I.V. infusion, the plasma to lymph filtration of total protein, albumin, and cholesterol was similar after duodenal infusion of either long-chain (LCT) or medium-chain (MCT) triglyceride. Filtration of cholesterol into intestinal lacteals was also measured after pulsed I.V. administration of 14C-β-sitosterol as an indirect marker for passage of lipoproteins into the lymph system. During intraduodenal administration of LCT and constant I.V. infusion of 125I-apo high density lipoprotein (HDL), intact plasma HDL appeared in lymph and contributed apo-LP to chylomicron formation. Nevertheless, most lymph apo-LP originated from local mucosal synthesis.
How to Cite:
Sipahi, A., Oliveira, H., Vasconcelos, K., Castilho, L., Bettarello, A. & Quintao, E., (1989) “CONTRIBUTION OF PLASMA PROTEIN AND LIPOPROTEINS TO INTESTINAL LYMPH: COMPARISON OF LONG-CHAIN WITH MEDIUM-CHAIN TRIGLYCERIDE DUODENAL INFUSION”, Lymphology 22(1), 13-19.
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