Articles

CLEANING THE BRAIN THROUGH TURBULENT GLYMPHATIC FLOW: THE WASHING MACHINE HYPOTHESIS

Author: P.H. Kuo (University of Arizona)

Abstract

LYMPHSPIRATION: In a thought experiment, a "washing machine" model is proposed based on turbulent flow from complex multi-dimensional forces to characterize fluid dynamics in the brain. The glymphatic system's hypothetical role in this system is illustrated in a series of diagrams. Implications of this model are discussed in terms of normal physiology and a variety of pathologic conditions such as brain atrophy and Alzheimer disease.

Keywords: glymphatic system, "washing machine" model, turbulent flow, meningeal lymphatics, cerebrospal fluid, brain atrophy, Alzheimer disease

How to Cite: Kuo, P. (2022) “CLEANING THE BRAIN THROUGH TURBULENT GLYMPHATIC FLOW: THE WASHING MACHINE HYPOTHESIS”, Lymphology. 54(3). doi: https://doi.org/10.2458/lymph.4787