@article{lymph 4616, author = {YK Hnin, LX Ong, CCC Tsai, SS Ong, SG Yee, BA Choo, JJH Low}, title = {DOES INITIAL ROUTINE USE OF A COMPRESSION GARMENT REDUCE THE RISK OF LOWER LIMB LYMPHEDEMA AFTER GYNECOLOGICAL CANCER TREATMENT? A RANDOMIZED PILOT STUDY IN AN ASIAN INSTITUTION AND REVIEW OF THE LITERATURE}, volume = {51}, year = {2019}, url = {http://journals.librarypublishing.arizona.edu/lymph/article/id/4616/}, issue = {4}, abstract = {<p>This is a randomized pilot study evaluating the effectiveness of customized compression garments (CG) in reducing the risk of lower limb lymphedema (LLL) in gynecological cancer patients. Patients who completed pelvic node dissection or radiation were routinely educated on reducing the risk of LLL by good skin care and manual lymphatic massage. After baseline lower limb volume perometry and clinical assessment, they were randomized to customized compression garment (CG) for 6 weeks (26 patients) or observation (30 patients). Both groups were followed up for 2 years and the primary outcome was the development of LLL. LLL incidence in the control group was 13.3% (4 of 30 patients) compared to 7.7% (2 of 26 patients) in the CG group. However the difference was not statistically significant (P=0.496). In the control group, 10.7% (3/28) who underwent node dissection developed LLL vs 7.7% (2/26) in the CG group. Among patients with node dissection plus radiation, LLL incidence was 14.3% (1/7) in the control group vs 12.5% (1/8) in the CG group. The mean onset of LLL was 12 months; compliance to CG wearing was high and QOL scores were similar in both groups. Customized low-compression CG worn for 6 weeks may have a possible benefit in reducing the risk of LLL when added to patient education on risk reduction although statistic significance was not achieved in this small pilot study. A larger multi-center study would be justified to expand these findings.</p>}, month = {5}, pages = {174-183}, keywords = {lower limb lymphedema,gynecologic cancer,compression garments,perometry}, issn = {2522-7963}, publisher={International Society of Lymphology and the University of Arizona Libraries}, journal = {Lymphology} }