Articles

FROM CHILDHOOD ONSET LYMPHEDEMA TO FATAL FETAL HYDROPS: POSSIBLE MODIFYING GENES FOR A FOXC2 MUTATION

Authors
  • LW Lai
  • RP Erickson
  • M Bernas
  • MH Witte

Abstract

We performed whole exome sequencing in a family with FOXC2 mutation where the phenotype in one generation was strikingly more severe. Although there were 3 mutations shared by 2 fatal fetal hydrops cases and not the mildly affected mother, none of them were likely to be the cause of the marked phenotypic change.

Keywords: lymphedema, fatal fetal hydrops, FOXC2, modifying genes

How to Cite:

Lai, L. & Erickson, R. & Bernas, M. & Witte, M., (2018) “FROM CHILDHOOD ONSET LYMPHEDEMA TO FATAL FETAL HYDROPS: POSSIBLE MODIFYING GENES FOR A FOXC2 MUTATION”, Lymphology 51(2), 85-88.

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Published on
05 Oct 2018
Peer Reviewed