Articles

The Possible Role of Dermal Lymphatics in the Dissemination of Breast Cancer

Authors
  • K Kett
  • I Kadas
  • L Tabar
  • L Lukacs

Abstract

The authors studied the role of the dilated cutaneous lymphatic capillaries, which function as a subsidiary draining system in advanced breast cancer in 7 patients. They selected the material by using the Patent blue dye test, then administered P32 isotope preoperatively for autoradiographic detection of tumour cell emboli in the mammary skin, excised by mastectomy. In half of the cases the histological follow-up of autoradiographically positive skin-samples showed the existence of cancer-cell nests in the minute lymphatics. They call attention to the fact, that the skin-area in question will not be removed totally by mastectomy, so that tumour cells which have become lodged in its dilated lymphatics may serve as a starting-point for local renewal and late dissemination. In support of their statement they bring some of their own observations.

How to Cite:

Kett, K. & Kadas, I. & Tabar, L. & Lukacs, L., (1972) “The Possible Role of Dermal Lymphatics in the Dissemination of Breast Cancer”, Lymphology 5(1), 37-41.

Downloads:
Download PDF

14 Views

10 Downloads

Published on
29 Sep 1972
Peer Reviewed