Studies on the Lymph Node-Venous Communications I. The Passage of Radioactive Serum Albumen
- R.F Dunn
- M.V. Burtz
- P.H. Ward
The passage of radioactive iodinated serum albumen (RISA) has been followed through the medial retropharyngeal lymph node of the dog by injecting RISA into one afferent lymphatic channel and assaying for radioactivity in samples recovered from the efferent lymphatic channel, the adjacent internal jugular vein, and distally from the femoral vein. Profiles of recovery from the efferent lymphatic and adjacent internal jugular vein showed a rapid, sharp rise in activity to a peak level followed by a rapid decline in activity. These peaks coincided with the injection time. A second recovery peak from the adjacent internal jugular vein also coincided with subsequent timed nodal palpation. Recovery from the femoral vein showed a steady increase to a plateau level which was reached after cessation of injection. The amounts of nodal retention and passage were quantitated to evaluate these parameters. A simplified hypothetical model is presented and discussed. The passage of RISA to the adjacent internal jugular vein indicates a direct lymph node-venous communication.
How to Cite:
Dunn, R. & Burtz, M. & Ward, P., (1972) “Studies on the Lymph Node-Venous Communications I. The Passage of Radioactive Serum Albumen”, Lymphology 5(1), p.15-23.