Articles

BILE CONSTITUENTS IN BLOOD AND LYMPH DURING BILIARY OBSTRUCTION II. THE ABSORPTION AND TRANSPORT OF BILE ACIDS AND BILIRUBIN

Authors: , , , ,

Abstract

The lymphatic and venous transport of bilirubin and total bile acid was examined in dogs after the occlusion of the common bile duct. Lymphatic concentrations of both substances attained maximum levels between the 4th and 6th hours, but remained during the entire time of observation (24 hours) above plasma concentrations.

The concentrations in blood plasma rose more slowly, but continuously. The amounts of both substances transported by the lymphatics rose steadly for 6 or 8 hours respectively and exceeded after 2 hours of occlusion the amounts transported by the veins. The results are explained by the changes in bilirubin and bile acid formation and secretion during biliary obstruction and on the basis of observations made in experiments with electrolyte and colloid infusions into the biliary passages.

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How to Cite: Szabo, G. , Magyar, Z. , Szentirmai, A. , Jakab, F. & Mihaly, K. (1975) “BILE CONSTITUENTS IN BLOOD AND LYMPH DURING BILIARY OBSTRUCTION II. THE ABSORPTION AND TRANSPORT OF BILE ACIDS AND BILIRUBIN”, Lymphology. 8(2).