Articles

THE FLOW RATE AND MACROMOLECULE CONTENT OF HILAR LYMPH FROM THE RABBIT'S KIDNEY UNDER CONDITIONS OF RENAL VENOUS PRESSURE ELEVATION AND RESTRICTION OF RENAL FUNCTION - STUDIES ON THE ORIGIN OF RENAL LYMPH

Authors
  • G Vogel
  • K Gartner
  • M Ulbrich

Abstract

The aim of this investigation was to ascertain whether renal lymph can be correctly thought of as mixed product consisting of protein-free fluid reabsorbed  from the renal tubules together  with  plasma.

By progressively compressing the terminal segment of the renal vein the hydrostatic pressure within it was raised to over 40 mmHg. The glomerular filtration rate (GFR) and the absolute amount of fluid reabsorbed fell simultaneously to 20% of their initial values. Lymph flow in a renal hilar lymphatic rose proportionately to renal vein pressure by a factor of up to 10. The concentrations of protein and poly­vinylpyrrolidone (PVP, MW 110,000) in the renal lymph remained unaffected at levels of 76 ± 13% and 56 ± 21% of their respective plasma concentrations. The intrarenal 131 I-albumin pool also remained un­ changed at 19.7 ± 4.3 ml plasma/100 g kidney. It is concluded that renal lymph is formed mainly by a filtration process from plasma. The results provide evidence against any admixture of protein-free reab­sorbed fluid with the renal lymph.

How to Cite:

Vogel, G. & Gartner, K. & Ulbrich, M., (1974) “THE FLOW RATE AND MACROMOLECULE CONTENT OF HILAR LYMPH FROM THE RABBIT'S KIDNEY UNDER CONDITIONS OF RENAL VENOUS PRESSURE ELEVATION AND RESTRICTION OF RENAL FUNCTION - STUDIES ON THE ORIGIN OF RENAL LYMPH”, Lymphology 7(3), 136-143.

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Published on
26 Sep 1974
Peer Reviewed