PULMONARY OXYGEN TOXICITY: INCREASED MICROVASCULAR PERMEABILITY TO PROTEIN IN UNANESTHETIZED LAMBS
- MS Bressack
- DD McMillan
- RD Bland
To study transvascular filtration of fluid and microvascular permeability to protein in the lung during prolonged hyperoxia, we measured lung lymph flow protein transport, and simultaneous pulmonary vascular pressures of six lambs breathing 100 percent O2 for five days. Lymph flow doubled, protein flow increased by 131 percent, and radioactive tracer studies demonstrated a clearcut increase in pulmonary microvascular permeability to protein after five days of continuous O2 breathing.
How to Cite:
Bressack, M. & McMillan, D. & Bland, R., (1979) “PULMONARY OXYGEN TOXICITY: INCREASED MICROVASCULAR PERMEABILITY TO PROTEIN IN UNANESTHETIZED LAMBS”, Lymphology 12(3), 133-139.