ROLE OF THE SPLEEN IN PNEUMOCOCCAL INFECTION
- SW Hosea
Complement and the spleen interact in host defense against the encapsulated Pneumococcus, responsible for most OPSI. Splenectomized patients lack splenic phagocytes specialized to clear bacteria coated with only small amounts of IgG from the bloodstream, and they are unable to mount a sufficient antibody response for liver macrophages to overcome the defect.
How to Cite:
Hosea, S., (1983) “ROLE OF THE SPLEEN IN PNEUMOCOCCAL INFECTION”, Lymphology 16(2), 115-120.