Articles

ENHANCED PROSTAGLANDIN I2-FORMATION OF HUMAN LYMPHATICS DURING PULSATILE PERFUSION

Authors: H Sinzinger ( ) , J Kaliman ( ) , E Mannheimer ( )

Abstract

Previous studies demonstrate that prostacyclin (prostaglandin I₂, PGI₂) is the main arachidonic acid product in human lymph vessels. Pulsatile perfusion increases and prolongs PGirfarmation as do leukotrienes (LT) such as LTC₄. Thus, physical activity besides local mechanical and biochemical influences on lymph pressure and flow also stimulates local lymphatic PGI₂ synthesis, a prime counterbalancing factor in lymphatic constriction induced by other eicosanoids.

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How to Cite: Sinzinger, H. , Kaliman, J. & Mannheimer, E. (1986) “ENHANCED PROSTAGLANDIN I2-FORMATION OF HUMAN LYMPHATICS DURING PULSATILE PERFUSION”, Lymphology. 19(4).