Articles
Authors: RV Cluzan ( ) , A Alliot ( ) , S Ghabboun ( ) , M Pascot ( )
Fifty seven patients with secondary lymphedema of the upper limb after previous treatment for breast cancer were treated for 3 months with an extract of Ruscus + Hesperidin Methyl Chalcone (CYCLO 3 FORT) or placebo according to a double-blind protocol in the context of a controlled clinical trial. All patients also underwent manual lymphatic drainage twice a week for at least one month. With CYCLO 3 FORT, the reduction in volume of arm edema, the main assessment criteria, was 12.9% after 3 months of treatment as compared with a placebo (p=0.009). Decreased edema tended to be more marked in the forearm compared with the upper arm where excess fat deposition seemed to dominate over excess fluid accumulation.
CYCLO 3 FORT was well tolerated with minimal adverse reaction.
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How to Cite: Cluzan, R. , Alliot, A. , Ghabboun, S. & Pascot, M. (1996) “TREATMENT OF SECONDARY LYM PHEDEMA OF THE UPPER LIMB WITH CYCLO 3 FORT”, Lymphology. 29(1).