Articles

CONTRIBUTION OF PLASMA PROTEIN AND LIPOPROTEINS TO INTESTINAL LYMPH: COMPARISON OF LONG-CHAIN WITH MEDIUM-CHAIN TRIGLYCERIDE DUODENAL INFUSION

Authors: AM Sipahi ( ) , HCF Oliveira ( ) , KS Vasconcelos ( ) , LN Castilho ( ) , A Bettarello ( ) , ECR Quintao ( )

Abstract

In rats with intestinal lymph-fistula and electrolyte and protein losses continuously replaced by I.V. infusion, the plasma to lymph filtration of total protein, albumin, and cholesterol was similar after duodenal infusion of either long-chain (LCT) or medium-chain (MCT) triglyceride. Filtration of cholesterol into intestinal lacteals was also measured after pulsed I.V. administration of ¹⁴C-β-sitosterol as an indirect marker for passage of lipoproteins into the lymph system. During intraduodenal administration of LCT and constant I.V. infusion of ¹²⁵I-apo high density lipoprotein (HDL), intact plasma HDL appeared in lymph and contributed apo-LP to chylomicron formation. Nevertheless, most lymph apo-LP originated from local mucosal synthesis.

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How to Cite: Sipahi, A. , Oliveira, H. , Vasconcelos, K. , Castilho, L. , Bettarello, A. & Quintao, E. (1989) “CONTRIBUTION OF PLASMA PROTEIN AND LIPOPROTEINS TO INTESTINAL LYMPH: COMPARISON OF LONG-CHAIN WITH MEDIUM-CHAIN TRIGLYCERIDE DUODENAL INFUSION”, Lymphology. 22(1).