Articles

CONTRIBUTION OF PLASMA PROTEIN AND LIPOPROTEINS TO INTESTINAL LYMPH: COMPARISON OF LONG-CHAIN WITH MEDIUM-CHAIN TRIGLYCERIDE DUODENAL INFUSION

Authors
  • AM Sipahi
  • HCF Oliveira
  • KS Vasconcelos
  • LN Castilho
  • A Bettarello
  • ECR Quintao

Abstract

In rats with intestinal lymph-fistula and electrolyte and protein losses continuously replaced by I.V. infusion, the plasma to lymph filtration of total protein, albumin, and cholesterol was similar after duodenal infusion of either long-chain (LCT) or medium-chain (MCT) triglyceride. Filtration of cholesterol into intestinal lacteals was also measured after pulsed I.V. administration of 14C-β-sitosterol as an indirect marker for passage of lipoproteins into the lymph system. During intraduodenal administration of LCT and constant I.V. infusion of 125I-apo high density lipoprotein (HDL), intact plasma HDL appeared in lymph and contributed apo-LP to chylomicron formation. Nevertheless, most lymph apo-LP originated from local mucosal synthesis.

How to Cite:

Sipahi, A. & Oliveira, H. & Vasconcelos, K. & Castilho, L. & Bettarello, A. & Quintao, E., (1989) “CONTRIBUTION OF PLASMA PROTEIN AND LIPOPROTEINS TO INTESTINAL LYMPH: COMPARISON OF LONG-CHAIN WITH MEDIUM-CHAIN TRIGLYCERIDE DUODENAL INFUSION”, Lymphology 22(1), 13-19.

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Published on
26 Nov 1989
Peer Reviewed