Intrasinusoidal erythroblast localisation in a case of secondary acute myeloid leukemia

Abstract

We report the case of a patient with myelodysplasia with excess blasts (MDS-EB) whose disease progressed into secondary acute myeloid leukemia (sAML), which was refractory to liposomal daunorubicin/cytarabine. His bone marrow trephine sections demonstrated unusual erythroblast localisation within the sinusoids, in addition to marked dysplasia. The role of these erythroblastic islands in acute myeloid leukemia is not well characterised. 

Keywords

Acute myeloid leukemia, morphology, bone marrow morphology, images, erythroblast, acute leukemia

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Mullen, C. G. & Doig, T. & Campbell, V. L., (2021) “Intrasinusoidal erythroblast localisation in a case of secondary acute myeloid leukemia”, Hematopathology 6(1), 18-19.

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Authors

Christopher Gerard Mullen (Edinburgh Western General Hospital)
Tamasin Doig (Edinburgh Western General Hospital)
Victoria Louise Campbell (Edinburgh Western General Hospital)

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Creative Commons Attribution-NonCommercial 4.0

Competing Interests

None.

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This article has been peer reviewed.

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