Abstract
Monosomy 7 or partial loss in the long arm of this chromosome is a recurrent nonrandom cytogenetic finding associated with a variety of hematological disorders. In the present case, a 9-month-old male presented with a febrile illness along with anemia and thrombocytopenia, and achieved spontaneous remission of the bicytopenia and monosomy 7 without any intervention 28 months after initial diagnosis. To our knowledge and literature search, this is likely the first case report of transient monosomy 7 in a patient with only bicytopenia. It is critical to closely monitor patients with monosomy 7 for evidence of spontaneous remission before proceeding to any major treatment.
Keywords
monosomy 7, bicytopenia, spontaneous remission, fluorescence in situ hybridization, karyotype
How to Cite
Yang, G., Rowsey, R. A., Wang, J., Ketterling, R. P. & Fisher, R., (2017) “Transient monosomy 7 associated with bicytopenia in a 9-month-old boy: Report of a case and review of the literature”, Hematopathology 2(1), 24-30.
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