MICROSPHERES IN CARDIAC LYMPH: CONTROL AND ISCHEMIC STATES
- LH Michael
- JR Hunt
- RM Lewis
- ML Entman
Abstract
The cardiac lymph from conscious animals was monitored for the presence or absence of radiolabelled 15 micrometer microspheres during: a) control periods after left atrial injection of microspheres and b) after circumflex coronary artery (CFX) occlusions (10-20 min total or < 40 mins 50% of control flow) followed by full reperfusions. Microspheres (15µ) numbering 7-150 were present in the lymph within 2 hrs after the occlusions; and in three experiments, the presence of a small number in the lymph on the following day implied continual release overnight. No microspheres were present in 8-48 hr lymph samples prior to occlusions. This study suggests that some microspheres escape from the intravascular spaze of the myocardium and are channeled into the cardiac lymphatics; this is apparent even after short-term ischemic events.
How to Cite:
Michael, L., Hunt, J., Lewis, R. & Entman, M., (1981) “MICROSPHERES IN CARDIAC LYMPH: CONTROL AND ISCHEMIC STATES”, Lymphology 14(3), 133-137.
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