Articles

INFLUENCE OF VENOUS CONGESTION ON BLOOD-LYMPH TRANSPORT OF FLUID AND LARGE MOLECULES IN THE HEAT-INJURED DOG'S PAW

Authors
  • E Renkin
  • C Sloop
  • W Joyner

Abstract

Hind paws of anesthetized dogs were exposed to moderate continuous heat (45-52°C). Lymph flow (L) was increased to 5.61 (SD 3.26) times control levels, lymph:plasma concentration ratios for total plasma protein (RT) were increased to 3.23 (SD 1.33), and for exogenous Dextran-110 (RD) to 8.41 (SD 4.00) times control levels. Selectivity of the blood-lymph barrier for individual plasma proteins was also decreased. Elevation of venous pressure during heating resulted in an increase of L in 5 out of 8 experiments, with no consistent change in RT or RD. Increased protein flux was thus closely coupled to increased volume flow. These observations are consistent with the presence and persistence of intercellular openings or gaps in the microvascular endothelium.

How to Cite:

Renkin, E. & Sloop, C. & Joyner, W., (1981) “INFLUENCE OF VENOUS CONGESTION ON BLOOD-LYMPH TRANSPORT OF FLUID AND LARGE MOLECULES IN THE HEAT-INJURED DOG'S PAW”, Lymphology 14(3), 113-117.

Downloads:
Download PDF

39 Views

26 Downloads

Published on
23 Sep 1981
Peer Reviewed