CLASSICS IN LYMPHOLOGY: THE PRODUCTION OF LYMPH
- EH Starling
Abstract
What makes a classic is both its timeliness and timelessness. By these criteria, Starling's epic work eminently qualifies. As can be gleaned from careful reading of his following "lecture" and other work, Starling not only recognized the forces regulating transcapillary fluid flux but fully anticipated issues surrounding macromolecular transport, regional variations in microvascular permeability, and "safety" factors forestalling edema (e.g. widened transcapillary oncotic gradient, accelerated lymph absorption and autoregulation of capillary pressure by reduction in arterial inflow during venous outflow block). A comprehensive up-to-date review of "our understanding of the wide variety of pathologic processes that share the common property of edema formation" has just been published (Edema: NC Staub and AE Taylor, Editors. Raven Press, 1984) embodying, embellishing, and advancing concepts first elucidated by Starling. (MHW)
How to Cite:
Starling, E., (1984) “CLASSICS IN LYMPHOLOGY: THE PRODUCTION OF LYMPH”, Lymphology 17(3), 83-88.
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