The many rare faces of follicular lymphoma – Part 1

Abstract

Follicular lymphoma (FL) is the most common well defined malignant lymphoma in the adults. Besides the classical pattern of effaced nodal architecture by back-to-back lymphoid follicles/nodules, it shows many morphological variations. Using actual cases, this article will illustrate the morphological features of these FL variants. In part 1, I will present 6 FL variants: 1) In situ FL and "early" interfollicular/partial nodal involvement by FL; 2) FL, floral variant ("cloudy variant"); 3) FL with abundant eosinophilic precipitate; 4) FL with marginal zone differentiation; 5) FL with plasmacytic differentiation; and 6) Pediatric FL. Pathologists should be familiar with these morphological variations to avoid mistakes in diagnosing FLs.

Keywords

Follicular lymphoma, morphologic variants

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Fratoni, S., (2016) “The many rare faces of follicular lymphoma – Part 1”, Hematopathology 1(1), 34-47.

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Authors

Stefano Fratoni (St. Eugenio Hospital of Rome, Italy)

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Creative Commons Attribution-NonCommercial 4.0

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This article has been peer reviewed.

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